A clinical trial including a researcher in the University of Arizona College of Medicine – Tucson’s Department of Psychiatry found that adding the medication aripiprazole to the antidepressant being taken by older patients with difficult-to-treat depression improved participant well-being and resulted in higher depression remission rates. The paper, “Antidepressant Augmentation versus Switch in Treatment-Resistant Geriatric Depression,” was published today in the New England Journal of Medicine.
“This study was designed to answer a continuing problem in our field,” said senior author Jordan F. Karp, MD, professor and chair of the Department of Psychiatry. “Any given treatment is likely to help only a subset of people, and ideally, we would like to know, in advance, who is most likely to be helped.”
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